INSERM U1016, Institut Cochin, Paris
- Doctorant moniteur
PARIS 13
2012 - 2015
Etude du Glioblastome et de l'effet des cellules souches cancéreuses sur la perméabilité vasculaire.
Directeur de thèse: Julie Gavard
Publications:
L Treps, S Edmond, E Harford-Wright, E M Galan-Moya, A Schmitt, S Azzi, A Citerne, N Bidère, D Ricard and J Gavard. Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma. 2015, Oncogene 317, 1-9.
S. Azzi, L. Treps, H. Leclair, H-M Ngo, E. Harford-Wright, J. Gavard. Desert Hedgehog/Patch2 Axis Contributes to Vascular Permeability and Angiogenesis in Glioblastoma. 2015, Frontiers in Pharmacology 6 00281, 1663-9812.
Dwyer J, Azzi S, Leclair HM, Georges S, Carlotti A, Treps L, Galan-Moya EM, Alexia C, Dupin N, Bidère N, Gavard J. The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity. 2015, Cell Commun Signal 15;13:11.
L Treps and J Gavard. L’angiogenèse tumorale : quand l’arbre de vie tourne mal. 2015, Médecine/sciences.
Blanco S, Dietmann S, Flores JV, Hussain S, Kutter C, Humphreys P, Lukk M, Lombard P, Treps L, Popis M, Kellner S, Hölter SM, Garrett L, Wurst W, Becker L, Klopstock T, Fuchs H, Gailus-Durner V, Hrabĕ de Angelis M, Káradóttir RT, Helm M, Ule J, Gleeson JG, Odom DT, Frye M. Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. 2014, EMBO J. 17;33(18):2020-39.
EM Moya, L Treps, J Gavard. Controlling the communication between brain endothelium and tumor initiating cells as a new therapeutic approach against glioblastoma. 2014, FEBS JOURNAL.
L Treps, A Le Guelte, J Gavard. Emerging roles of semaphorins in the regulation of epithelial and endothelial junctions. 2013, Tissue Barriers 1(1).
E Galan-Moya, L Treps, L Oliver, H Chneiweiss, F M. Vallette, N Bidère, J Gavard. Endothelial Secreted Factors Suppress Mitogen Deprivation-Induced Autophagy and Apoptosis in Glioblastoma Stem-Like Cells. 2014, Plos One.
Inserm
- Stagiaire M2
PARIS 13
2012 - 2012
Etude des marqueurs des vaisseaux tumoraux dans les Glioblastomes humains.
Equipe J. Gavard, INSERM U1016, Cnrs UMR8104
Publication: A Le Guelte, E Galan-Moya, J Dwyer, L Treps, G Kettler, J K Hebda, S Dubois, C Auffray, H Chneiweiss, N Bidere, J Gavard. Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation. 2012, J. Cell Science.
The Wellcome Trust Centre for Stem Cell Research, Cambridge
- Stagiaire M2
2011 - 2012
Etude de la méthyltransferase NSun2 et de l'endonucléase Elac2 dans le clivage des ARNt suite au stress oxydatif des kératinocytes murins.
Equipe M. Frye, CSCR, Austin Smith Institute
Publications: S Blanco, S Dietmann, J V Flores, S Hussain, C Kutter, P Humphreys, M Lukk, P Lombard, L Treps, M Popis, S Kellner, S M Hölter, L Garrett, W Wurst, L Becker, T Klopstock, H Fuchs, V Gailus‐Durner, M Hrabĕ de Angelis, RT Káradóttir, M Helm, J Ule, J G Gleeson, D T Odom, M Frye. Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders. 2014. The EMBO journal.
