Pierre Sae Houer

Ph.D. in Pharmaceutical Science and Pharmaceutical formulation
Conception and optimization of lipid-based systems intended to oral administration
Supervised by Pr Thierry VANDAMME at the Faculty of Pharmacy (Louis Pasteur University)
Main responsibilities:
- Establishment of a cell culture room for the laboratory (contacting equipments and consumables suppliers, redaction of SOP, management and maintenance of the equipments…)
- Development of protocols used to assess the cytotoxicity of lipid-based excipients.
- Investigation of different lipid-based systems (SEDDS, SMEDDS) on intestinal permeability enhancement.
- Teaching, training and supervising of many student trainees.

Transfer of a production line from the Danish to the Swiss manufacturing plant within the production department
At the manufacturing department and supervised by François HOSOTTE
Main responsibilities:
- Assisting the Project Team to implement and optimize the granulation, coating and tabletting process lines by generating SOP, the first version of batch report templates and the draft of the cleaning validation protocol.
- Training of the operators on the manufacturing and cleaning procedures.
- Being one of the link persons between the Project Team, the Maintenance & Engineering and the production department.

Determination and optimization of a method to distinguish chocolate of different origins by gas chromatography analysis of their aroma (GC-FID)
At Faculty of Pharmacy (Louis Pasteur University) and supervised by Pr MARCHIONI
Main activities:
- Extraction of the aroma of chocolates coming from three different origins.
- Optimization of a chromatographic method used to analyse the aroma.

Investigation of different cyclosporine A formulations intended to ocular administration on the treatment of cornea graft rejections and ocular inflammations
At the ophthalmology department and supervised by Pr FLAMENT.
Main activities:
- Analysis of the effects of different formulations on the improvement of the patient’s condition.
- Proposition of a manufacturing process for the pharmacy department.