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Jérôme JACQ

NIVELLES

En résumé

 Expertise in flow chemistry: synthesis, equipment (synthetic, downstream processes & analysis)
 Development & methodology in organometallic chemistry
 Multi-stage synthesis & medicinal chemistry: elaboration of a library of bioactive compounds
 Participation in some multi-disciplinary collaborations


Mes compétences :
Chimie
chemical development
Quality Control
Microsoft SharePoint
Microsoft Office
HPLC
First experience
Derivatives
Automation Skills

Entreprises

  • UCB Pharma - Post-doctoral Scientist

    2011 - maintenant UCB Pharma (Braine L'Alleud, Belgium) - Chemical Research Department - High throughput organic synthesis group, managed by Dr. Pasau.
    Set up of a microfluidic/flow chemistry platform.

    Flow chemistry applied to multistep synthesis, asymmetric reactions, reactive intermediate synthesis, scale-up processes - Automation development for library productions and reaction optimisations - Installation of flow synthesis equipment (commercial and homemade), downstream tools and development of custom analytic tools.

  • University of Waterloo - Research Assistant

    2010 - maintenant Scope and mechanism of Pd-catalysed hydrogenolysis of unstrained Csp3-Csp3 bonds.


    Mechanistic studies: kinetic & deuterium labelling experiments (2H RMN) – Organometallic projects (glove box).

  • University of Waterloo (Ontario, Canada) - Post doctoral Position

    2010 - 2010 Post-doctoral position - University of Waterloo (Ontario, Canada), Dr. Fillion's Group.
    Scope and mechanism of Pd-catalysed hydrogenolysis of unstrained Csp3-Csp3 bonds.

    Mechanistic studies: kinetic & deuterium labelling experiments (2H RMN) - Organometallic projects (glove box).

  • Université Joseph Fourier - Ph. D. in synthetic organic chemistry

    Saint-Martin-d'Hères 2006 - 2009 Ph. D. in synthetic organic chemistry at Dr. E. Greene's research group (DCM: Département de Chimie Moléculaire) under the supervision of Dr. Einhorn (
    Synthesis and biological properties of N-hydroxyimides, inhibitors of protein-kinase.

    Medicinal chemistry project - Preparation and use of organometallic derivatives & air-sensitive compounds - Microwave synthesis - Analytical chemistry (HPLC, GC-MS, NMR, ...).

  • Oril industrie - Junior engineer internship

    2006 - 2006 chemical development managed by Dr. Vaysse-Ludot and Dr. Hardouin.
    Studies on processing of pharmaceutical compounds.

    First experience in pharmaceutical industry & in development- Exploring a new chemical approach to pharmaceutical candidates.

  • Departement de Chimie Moleculaire, Grenoble - Ph. D. in synthetic organic chemistry

    2006 - 2009 at Dr. Andrew E. Greene’s research group, under the supervision of Dr. Jacques Einhorn.

    Synthesis and biological properties of N-hydroxyimides, inhibitors of protein-kinase.

    Medicinal chemistry project - Preparation and use of organometallic derivatives & air-sensitive compounds - Microwave synthesis - Analytical chemistry (HPLC, GC-MS, NMR, …

  • Oril Industrie, Servier - Bolbec, France. - Junior Engineer

    2006 - 2006 Internship in chemical development managed by Dr. Vaysse-Ludot and Dr. Hardouin
    Studies on processing of pharmaceutical compounds

    First experience in pharmaceutical industry & in development - Exploring a new approach to pharmaceutical candidates

  • The Thomas Bata University - Research internship

    2005 - 2005 Structure and properties of specifically nucleated polypropylene.

  • Thomas Bata University (Zlin, Czech Republic) - Research training

    2005 - 2005 Structure and properties of specifically nucleated polypropylene

  • Degussa - Technician

    2004 - 2004

Formations

Réseau

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